Rules for Nuclear Localization Sequence Recognition by Karyopherinβ2
نویسندگان
چکیده
منابع مشابه
Rules for Nuclear Localization Sequence Recognition by Karyopherinβ2
Karyopherinb (Kapb) proteins bind nuclear localization and export signals (NLSs and NESs) to mediate nucleocytoplasmic trafficking, a process regulated by Ran GTPase through its nucleotide cycle. Diversity and complexity of signals recognized by Kapbs have prevented prediction of new Kapb substrates. The structure of Kapb2 (also known as Transportin) bound to one of its substrates, the NLS of h...
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ژورنال
عنوان ژورنال: Cell
سال: 2006
ISSN: 0092-8674
DOI: 10.1016/j.cell.2006.05.049